Scientists have found a mechanism linking smoking to pancreatic cancer development via immune dysregulation. The study demonstrates that components in cigarette smoke, specifically aryl hydrocarbon receptor ligands (AhRLs), promote pancreatic cancer initiation and progression by altering immune responses, particularly through effects on CD4+ T cells, leading to immune dysregulation.
Seeking commentary, including:
(1) What are the implications of these findings?
(2) What should smokers do in response to these findings?
(3) What tips would you offer people who want to quit smoking?
posted9/4/2025
deadline9/15/2025
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